SIK1 and metabolic syndrome: Genetic variants in SIK genes also have been linked with alterations in blood lipid panels, suggesting the potential clinical relevance of SIK genes for dyslipidemia (Chasman et al., 2008; Teslovich et al., 2010; Braun et al., 2012; Willer and Mohlke, 2012; Ko et al., 2014; Karjalainen et al., 2020).