Data from the first sick day of patients with liver cirrhosis were analyzed using the Child–Pugh classification system as follows: Grade A: 34 cases 25.0 ± 28.0 ng/mL; Grade B: 18 cases 48.2 ± 65.8 ng/mL; Grade C: 9 cases 70.2 ± 56.7 ng/mL; as grade increased, urinary NGAL was noticeably higher (Fig. 4a). This evidence concerns the gene LCN2 and cirrhosis of liver.