DAPK-1 has both pro-apoptotic and anti-apoptotic properties [1,13] and a connection has been established between the expression of DAPK-1 and Fas-mediated apoptosis (Fas is a membrane protein belonging to the death receptor family. Cross-linking of Fas by its ligand, FasL, or agonistic anti-Fas antibodies, induces apoptosis of cells expressing Fas on the membrane by triggering a cascade of caspases) in human endometrial adenocarcinoma cells, shedding light on the role of DAPK-1 in promoting the survival of tumor cells [1]. The gene discussed is FAS; the disease is endometrium adenocarcinoma.