The patient exhibited significant hair loss, low complement levels (C3: 0.31 g/L; C4: 0.04 g/L), pleural and pericardial effusions, and renal involvement (serum creatinine: 101 μmol/L; 24-hour urinary total protein: 1.13 g/L). This evidence concerns the gene C4A and pericardial effusion.