The most common grade ≥ 3 irAEs were elevated AST (6.2%), hypertension (5.3%), elevated ALT (4.3%), thrombocytopenia (4.0%), hyperbilirubinemia (3.9%), proteinuria (3.4%), increased γ-glutamyltransferase (3.2%), neutropenia (2.6%), gastrointestinal bleeding (2.5%), and hand–foot skin reaction (2.3%). The gene discussed is GPT; the disease is Thrombocytopenia.