SMARCA4 expression was positively correlated with multiple NE genes including SYP, CHGA, INSM1, DLL3 and NCAM1 and negatively correlated with non-NE factors REST, NOTCH2, and YAP1 in both SCLC cell lines and patient tumor databases (Figs. 1C and S1A). This evidence concerns the gene REST and small cell lung carcinoma.