Notably, higher plasma GFAP concentrations were unrelated to more cortical Aβ plaque accumulation or hippocampal atrophy, nor did they influence the association of plasma Aβ42/Aβ40 and plasma p-Tau181 with cortical Aβ plaque accumulation or hippocampal atrophy. The gene discussed is GFAP; the disease is hippocampal atrophy.