GFAP and dementia: A recent 17-year longitudinal study involving 1712 CU participants found that serum GFAP levels at baseline were associated with a hazard ratio of 1.38 (95% confidence interval = 1.15–1.66) for incident dementia and 2.76 (95% confidence interval = 1.73–4.40) for dementia-specific mortality, supporting the notion that circulating GFAP can be a valuable tool for assessing dementia risk and prognosis [118].