Features contributing to latent variable 2 include the DNAm sites cg05479174, within an exon of SFSWAP, and cg06635176 within an intron of AGBL4. IL20RB (interleukin 20 receptor subunit beta) mRNA was upregulated in non-progressive sarcoidosis, while ABCC11 (ATP binding cassette subfamily C member 11) expression was higher in progressive sarcoidosis. The gene discussed is AGBL4; the disease is sarcoidosis.