Additionally, despite observing a high level of gene expression associated with the positive regulation of immune-related molecules (such as Stat1, Irgm, Gbp, Cxcl9), and IFNG-related molecules (such as Gbp, Igtp, Ligp1, Tgtp1 genes) in the light group, tumor growth was not inhibited due to the absence of effective immune cells in NCG mice. The gene discussed is IRGM; the disease is neoplasm.