CD274 and neoplasm: Moreover, non-tumor invaded TDLNs (TDLNs−) are enriched for tumor-specific PD-1+ T cells, abundant PD-1/PD-L1-interactions derived from conventional dendritic cells (cDCs) and tumor-specific PD-1+ T cells but not tumor, are correlate with early distant disease recurrence, and PD-L1 blockade on cDCs elicits effective antitumor immunity9.