Pathological mutations in NUP93 have been implicated in early-onset, severe kidney diseases, such as SRNS and focal segmental glomerulosclerosis (FSGS), with studies revealing its essential role in kidney cell function (Braun et al. 2016; Bierzynska et al. 2022; Dhanorkar et al. 2023; Hashimoto et al. 2019; Wasilewska et al. 2023). The gene discussed is NUP93; the disease is focal segmental glomerulosclerosis.