NUP98 and acute myeloid leukemia: Interestingly, the upstream region of human NUP96 is the NUP98 coding region, and NUP98 chromosomal translocation (fusion with the Homeobox A9 (HOXA9) gene) has been observed in patients with acute myeloid leukemia (AML) (Nakamura et al. 1996; Borrow et al. 1996).