The other retinoblastoma had multiple genomic abnormalities on chromosomes 6, 7, and 8, in line with chromothripsis, chromoanasynthesis or chromoplexy including an amplification containing the downstream MYC(N) signaling component, BRAF (Supplementary Fig. S2b, c, Supplementary Data 3). This evidence concerns the gene BRAF and retinoblastoma.