In the sub-analysis for diabetes type, we found that an inflammatory environment was generally present in both diabetes types, although the point estimates were generally lower for the type 1 diabetes group than the type 2 diabetes group, except for human monocyte chemoattractant protein 4 (MCP-4), which had a point estimate of 54% (95% CI 14, 110%) for type 1 diabetes vs 35% (95% CI 16, 57%) for type 2 diabetes (ESM Fig. 3). This evidence concerns the gene CCL13 and type 2 diabetes mellitus.