SCGB1A1 and asthma: In this study, we generated CC10 gene-deficient (Cc10−/−) mice, and then utilized a house dust mite (HDM)-induced murine asthma model and cultured bone marrow-derived dendritic cells (BMDCs), to evaluate the role of CC10 in alleviating Th2-mediated airway inflammation in asthma and its effects on the differentiation phenotype and immune activation functions of lung DCs and BMDCs.