MTOR and atherosclerosis: Immunosuppressant agents, particularly m-TOR inhibitors,are known to limit atherosclerosis progression in Ktx recipients by exerting adirect effect on immune cells at the vascular wall level [30]; by the same token,a similar inhibitory effect on CatK expression cannot in principle be excluded.Nevertheless, all study participants were under chronic immunosuppressive therapyand no differences in the rate of different medications prescribed were noticedbetween the two study subgroups.