FGF21 and liver dysplastic nodule: Significant negative correlations were observed between the changes in FGF21levels and BMI (r = –0.4, p = 0.03) (Fig. 2a), between changes in FGF21and the improvement of CPT values (r = –0.58, p < 0.001) (Fig. 2b)and between the changes in FGF21 and TNF-alpha levels (r = –0.46, p =0.01) in DN patients after 6-week physical activity (Fig. 2c).