Rodent model studies have underlined the role of inflammation in HF, suggestingits unfavourable impact on cardiac homeostasis [80, 81, 82, 83], also showing acorrelation with pro-inflammatory cytokines blood levels, such as tumor necrosisfactor (TNF)-α, IL-6, and IL-1β, and HF severity [84]. The gene discussed is IL1B; the disease is hydrops fetalis.