The hepatic steatosis index (HSI), which is calculated using the formula HSI = 8(alanine aminotransferase [ALT]/aspartate aminotransferase [AST] ratio) + bodymass index (BMI) (+2, if female; +2, if diabetes) was originally used to evaluatehepatic steatosis [12]. The gene discussed is GPT; the disease is Hepatic steatosis.