The renin angiotensin system (RAS) plays a very important role in regulatingnormal physiology and the mechanisms of cardiovascular disease development.Angiotensin converting enzyme (ACE) is an important key enzyme of the classicalRAS pathway angiotension converting enzyme-angiotensin II-type 1 (ACE-Ang II-AT1), which converts angiotensin (Ang) I to Ang II, and theincrease in Ang II is an important part of the RAS involved in the development ofcardiovascular diseases. The gene discussed is AGT; the disease is glycogen storage disease VI.