GDF15 and coronary artery disorder: Previous studies have shown, that the physiological effect of GDF-15 is highlycontext-dependent and can vary significantly with the stage of disease [29].Therefore, we would like to use this review to summarize the actual existingresearch data and focus on the effect of GDF-15 in different cell types withspecial reference to cellular stress and inflammation to better understand thesignaling pathways of GDF-15 in coronary artery disease (CAD).