GPT and hypertensive disorder: The most common G3-5 toxicities included diarrhoea 4.8% (47/964), Rash 7.1% (68/964), AST increase 6.3% (61/964), ALT increase 5.6% (54/964) with less common toxicities of Fatigue 2.5% (23/904); SOB 2.2% (12/540); Hypertension 1.9% (6/312).