It could be that the number ofpatients without diabetes and with significant vascular stiffness was too low.Finally, the correlation between RBP4, arterial stiffness and clinical outcomeshad not been investigated, so further clinical studies are needed to understandwhether reducing RBP4 levels in diabetic patients with CHD may actually have animpact on prognosis. The gene discussed is RBP4; the disease is coronary artery disorder.