Multiple biomarkers that reflect myocardialinjury, heart failure, and inflammation (e.g., troponin I, N-terminal pro-B-typenatriuretic peptide, and C-reactive protein, respectively) have been investigatedand proved to improve the predictive performance of models that includetraditional risk factors of CVD [27, 28, 29, 30]. This evidence concerns the gene CRP and heart failure.