NPPB and atrial septal defect: Similarly, a TBIL level of 10.35 mg/dLoffers a sensitivity of 89.3% and a specificity of 62.2% in differentiatingbetween the two groups (AUC: 0.788, 95% CI: 0.685–0.890, p< 0.001).Furthermore, UA levels exceeding 407 μmol/L distinguish SPAHpatients from the general ASD population with a sensitivity of 50.0% and aspecificity of 90.5% (AUC: 0.693, 95% CI: 0.563–0.824, p = 0.003).Additionally, an NT-proBNP cutoff value of 187.5 pg/mL provides a means todifferentiate SPAH patients from ASD patients with a sensitivity of 71.4% and aspecificity of 87.5%.