FSTL1 and myocardial infarction: Higher levels ofFSTL1, Wingless-type inducible signaling pathway protein 1 (WISP1), and asprosinwere noted in obese or diabetic patients compared with normal controls, therebysuggesting their potential role in the development of these conditions.Conversely, secreted frizzled-related protein 5, Metrnl, Neuregulin-4, and familywith sequence similarity 19 member A5 may serve as protective factors [122].FSTL1 may ameliorate cardiac dysfunction in MI by inhibiting myocardial fibrosisand apoptosis through upregulation of FSTL1/USP10/Notch1 signaling [123].