TTR and cardiac amyloidosis: This protein is a tetramer, but has an innateability to dissociate into monomers which tend to be amyloidogenic properties.There are three main types of CA: immunoglobulin light chain cardiac amyloidosis(AL-CA), wild-type transthyretin cardiac amyloidosis (ATTRwt-CA) and mutanttransthyretin cardiac amyloidosis (ATTRm-CA) [3].