Another index patient diagnosed with RCM at the age of 23and died due to progression of congestive heart failure at the age of 28indicated a deletion of one nucleotide g.4762delG in exon 7 of TNNI3.This deletion also induced a frameshift in residue 168 and the introduction of apremature termination codon at site 176 (D168fsX176) [24]. Here, TNNI3 is linked to cardiomyopathy, familial restrictive, 1.