However, the COVID-19 mRNA vaccine has also been associated with anincreased incidence of relatively rare diseases, such as myocardial injury,myocarditis thrombosis, tubulitis, macrovasculitis and Kawasaki disease [5, 6, 7, 8, 9, 10, 11, 12, 13, 14].It has been established that the COVID-19 mRNA vaccine produces antibodies to Sprotein through mRNA and membrane s glycoprotein, prevents the binding of Sprotein with angiotensin converting enzyme2 (ACE2), and produces cellular immunityand humoral immunity, which eventually leads to myocarditis [15]. The gene discussed is ACE2; the disease is COVID-19.