Considering the instrumental rolethat the Mox-LDL-LOX-1 signaling axis may have in the development and advancementof atherosclerosis and other related diseases, mainly CD, targeting thisinteraction would be extremely promising for the development of anti-atherogenictherapeutic strategies to prevent and manage ischemic strokes and theircomplications. The gene discussed is OLR1; the disease is ischemic stroke.