These observations could have importantimplications regarding the negative and dual role that Mox-LDL may play inatherogenesis and CD where it may be involved in regulating the divergent effectsof tPA and decreasing the inhibitory and neuroprotective capacity of neuroserpinthrough preferably binding to the lox-1 scavenger receptor; both processes aredeleterious to ischemic neurons after stroke. Here, PLAT is linked to Stroke.