The best predictive model was determined using stepwise Cox regression(including age, sex, history of hypertension, history of AF, NYHA class,haemoglobin levels, sodium concentration, log-transformed NT-ProBNP, and therapywith ACEI/ARB and β-blockers) which yielded a c-index of 0.726 for theoverall cohort of patients with DCM. The gene discussed is NPPB; the disease is familial dilated cardiomyopathy.