Acromelic dysplasia caused by fibrillin 1 (FBN1) gene mutation is an autosomal dominant disorder, consisting of acromicric dysplasia (AD, OMIM #102370), geleophysic dysplasia 2 (GD2, OMIM #614185), and Weill-Marchesani syndrome 2 (WMS2, OMIM #608328) (1). This evidence concerns the gene FBN1 and Alzheimer disease.