Finally, SOAE(100 and 300 μg/mL, in RAW cells) also affected lipid metabolism byregulating genes involved in RCT, such as ABCA1 andliver X receptors (LXRs, transcription factors involved in the ABCA1 induction).Altogether these findings confirmed the three major mechanisms by which sesameoil could inhibit atherosclerosis [142]. Here, ABCA1 is linked to atherosclerosis.