Bhaskaran et al. [166] demonstrated beneficial effectof sesame oil consumption (atherogenic diet with sesame oil, 170 g/kg for 12weeks) manifested by the reduction of the atherosclerotic lesion formation andplasma cholesterol, TG, and LDL-C levels in male LDLR-/- mice (LDL receptorknock-out mice with pre-existing atherosclerosis). The gene discussed is LDLR; the disease is atherosclerosis.