Notably, while there were no significant differences in the MFI of IFN-γ-producing CD8+ T cells at 1 week post-infection, wildtype mice infected with L. major alone or in combination with LeishEXO exhibited higher IFN-γ levels than ANXA1-deficient mice infected with the parasite alone at the 5 week time point (Supplementary Figure S3B). This evidence concerns the gene CD8A and infection.