In aprospective study of 60 patients with severe AS and also echocardiogaphicallydetermined PH, Gumauskienė et al. [29] examined NT-proBNP and GDF-15.This working group chose the cut-off for the presence of PH at an sPAP ≥45mmHg, slightly higher than in the present cohort. Here, GDF15 is linked to aortic valve stenosis.