PDZK1IP1 and aortic valve stenosis: To strengthen the significance of sPAP as an important non-invasive parameter,in the present study, patients with severe AS planned for TAVR procedure wereexamined echocadiographically for the potential presence of PH (sPAP ≥40mmHg) and the expression of various cardiovascular biomarkers was assessed inrelation to sPAP.