Currentcardiovascular research is focused primarily on finding and targeting molecularpathways and inflammatory markers underlying atherosclerosis that would beclinically effective in improving outcomes in cardiovascular patients.Experimental and clinical research point to the NLRP3inflammasome/IL-1β/IL-6/CRP pathway, important for targeted andnon-targeted drug therapy in coronary artery disease. This evidence concerns the gene IL1B and atherosclerosis.