AGT and cardiac hypertrophy: Furthermore, angiotensin 1–7 has a potential role to attenuate atrialtachycardia events by (1) decreasing the potential action duration via reducedexpression of L-type calcium channel and outward potassium channel [54]; (2)preventing fibrotic process in the atrial wall, which predisposed to atrialtachycardia [54]; and (3) decreasing the norepinephrine release fromhypothalamus, which resulted in the attenuation of sympathetic stimulation [55].Angiotensin 1–7 can also prevent myocardial hypertrophy, and left ventricularthinning, and reduce myocardial infarct area in the post-MI setting [56].