CCR2 and triple-A syndrome: Moreover, Zhanget al. [59] revealed that chemokine (C-C motif) receptor 2 (CCR2) is thekey chemokine receptor for mast cell recruitment in Ang II-induced AAA lesions.Similarly, CCR2 knockout in mast cells protected from AAA by decreasingangiogenesis, macrophage and T cell infiltrations, and medial smooth muscle cellloss [59].