The final established SAE risk calculation formula waslogit(p) = –6.134 + 0.992 × pulmonary artery hypertension+ 1.459 × disease severity (severe) + 2.324 × procedure type(diagnostic and interventional) + 1.436 × cTnI (≥0.028μg/L) + 1.537 × NT-proBNP (≥126.65 pg/mL). The gene discussed is TNNI3; the disease is pulmonary arterial hypertension.