SLC9A1 and cardiac hypertrophy: In addition to the gliflozins, teneligliptin, adipeptidyl peptidase-4 inhibitor used for the treatment of type 2 diabetes insome countries has been shown to reduce cardiac hypertrophy and the concomitantincrease in NHE1 expression in spontaneously hypertensive rats that wasattributed to normalization of the elevated plasma angiotensin II levels observedin these animals [359].