TNFSF10 and neoplasm: Combined treatment with acetylshikonin and TRAIL significantly reduced the number of tumour nodules in the livers of mice, with the number of tumour nodules in the treatment group being 2.7 times that of the control group. There was no significant difference in body weight changes between the two groups of mice, suggesting that the combined treatment of acetylshikonin and TRAIL had no significant cytotoxicity in mice