POU5F1 and neoplasm: DC(I + II) NPs repressed stemness genes (NOTCH1, WNT1, chemoresistance gene, prominin1, SOX2, OCT-4, and NANOG), GSTP1, telomerase, MMP9-stimulated metastasis, VEGFA, and cyclin D-mediated cell cycle by two to six folds, 5 folds, 2 folds, two to three folds, two to three folds, and two to four folds, respectively, in both tumor tissues (Figures 6A–C).