Furthermore, serum galectin-3 levels (odds ratio [OR]:1.056, 95% confidence interval [CI]: 1.003–1.112, p = 0.037) and CRP(per 0.1 mg/dL increment, OR: 1.195, 95% CI: 1.032–1.383, p = 0.017)were identified as independent predictors of PAD. Here, LGALS3 is linked to peripheral arterial disease.