Patients with low ABIs had a greater prevalence of DM(p = 0.011), elevated CRP and galectin-3 levels (both p<0.001), and lower creatinine (p = 0.012), but no significant disparitiesin gender, hypertension prevalence, smoking, blood pressure, HD vintage, or Kt/Vwere observed between groups. The gene discussed is CRP; the disease is hypertensive disorder.