STAT6 and cardiac hypertrophy: It regulatespressure overload-induced cardiac hypertrophy and ECM remodeling through thefibrosis signaling pathway involving signal transducer and activator oftranscription 3 (STAT3) and signal transducer and activator of transcription 6(STAT6) in macrophages, resulting in an increase in the anti-inflammatory/M2macrophage phenotype.