rs7257062 was foundto be an independent risk factor of CAD (OR = 1.581, 95% CI: 1.094–2.284,p = 0.015) in a multivariable logistic analysis, after controlling forpotential confounders including gender, smoking history, diabetes, hypertension,TG, TC, HDL-C, LDL-C and ApoB. The gene discussed is APOB; the disease is hypertensive disorder.