Multivariable logistic analysis, controlling for gender, age,body mass index (BMI), triglycerides (TG), TC, HDL-C, LDL-C, ApoA and ApoB,demonstrated that rs7257062 was still an independent risk factor of CAD(OR = 1.499, 95% CI: 1.036–2.168, p = 0.032). This evidence concerns the gene LPA and coronary artery disorder.