Studies on lipid metabolism disorders andinflammatory responses due to the regulation of gene expression have shown thatthere is as yet an undefined association between fatty acid desaturases, they areregulated by the FADS gene cluster, and AS, whereby fatty acid desaturaseexpression levels, as well as its activity, can differentially affect AS [13, 14, 15].Based on existing studies, the effect of polyunsaturated fatty acid metabolism onatherosclerosis remains in the exploratory stage. This evidence concerns the gene SCD and aortic valve stenosis.