FADS2 and aortic stenosis: A GWAS of 44703 participants in the Genetic EpidemiologyResearch on Adult Health and Aging (GERA) cohort, one of the largest collectionsof aortic stenosis in the world, demonstrated that theFADS1/FADS2 locus variants (rs174547) are associatedwith aortic stenosis, while higher levels of AA and a higher ratio of AA/LA wereassociated with increased odds of calcification of the aortic valve leaflets[68].