CASP8 and familial dilated cardiomyopathy: Autophagy and apoptosis are often associated in the pathological process of DCM.Scutellarin can promote the autophagy signaling pathway by up-regulatingautophagy-related factors (Beclin-1 and LC3-II) and inhibit the apoptotic signalpathway by down-regulating apoptosis-related factors (caspase-3, caspase-8,caspase-9, caspase-12, Bax, and Cyt-C), thereby relieving DCM [52].