For instance, NRF2can modulate the activity of GPX4 and iron homeostasis by targeting solutecarrier family seven member 11 (SLC7A11), contributing to ferroptosis resistanceby reducing the level of lipid peroxidation in myocardial infarction [40].Additionally, lncRNA metastasis-associated lung adenocarcinoma transcript 1(MALAT1) has been found to be up-regulated in hypoxia/reoxygenation-treatedcardiomyocytes and rat heart tissue. Here, GPX4 is linked to myocardial infarction.