When comparing the high LVEF-HFpEF group to the HFrEF group,significant differences were observed in age, sex, systolic blood pressure, HR,baseline LVEDD, baseline LVESD, NYHA class III/IV, AF, hypertension,hyperuricemia, ACEI/ARB/ARNI usage, CCB usage, β-blocker usage,aldosterone receptor antagonist usage, diuretic usage, antiplatelet medicationusage, digitalis usage, hemoglobin levels, and creatinine levels (p<0.05) (Table 1). This evidence concerns the gene NR3C2 and atrial fibrillation.