Therefore, the expression of ANPand BNP genes (as markers of cardiac hypertrophy), TGF-βand collagen genes (as markers of cardiac fibrosis), RyR andSERCA genes (as an indicator of intracellular calcium homeostasis),PGC-1α and AMPK genes (as an indicator ofmitochondrial function) and echocardiography parameters were assessed to clarifythe preventive effects of exercise on DCM. This evidence concerns the gene PPARGC1A and familial dilated cardiomyopathy.