In addition, pathological hypertrophy of the heart followingcardiac fibrosis is associated with the activation of fetal genes likebrain natriuretic peptide (BNP) and atrial natriureticpeptide (ANP) and that enhances lengths or widths of cardiomyocytes andcontributes to the development of DCM [3]. The gene discussed is NPPB; the disease is familial dilated cardiomyopathy.