RYR2 and familial dilated cardiomyopathy: Therefore, the expression of ANPand BNP genes (as markers of cardiac hypertrophy), TGF-βand collagen genes (as markers of cardiac fibrosis), RyR andSERCA genes (as an indicator of intracellular calcium homeostasis),PGC-1α and AMPK genes (as an indicator ofmitochondrial function) and echocardiography parameters were assessed to clarifythe preventive effects of exercise on DCM.