Different types of BAsact as signaling molecules on regulating lipid levels of the host via itsreceptor farnesoid X receptor (FXR) and the Takeda G protein-coupled bile acidreceptor (TGR5) mediated signaling pathway [14], and are considered as apotential target in the treatment of hyperlipidemia [15]. Here, NR1H4 is linked to hyperlipidemia.